Back in time – Day 22

Over the last nine days through all of our experimenting Wyatt has only had an average of about a 30% reduction in seizures. This is making me want to go back in time to Days 4 and 5 where we saw the best control – around 70%. I am going to try to recreate that day with the same dosing and cohort A. We’ll also try to tease our which strain in A is most effective. We have just over a week left here in Oregon and we want to try to maximize control if we can.

C didn’t deliver as much as I wanted it to in reducing intensity so we took that cohort out of the equation for now.

There seems to be so much potential here and lots of options (we have very quickly tried 15 strains in the three different infusions and there are more that have helped folks with seizures) but we are running out of time to experiment and it breaks my heart.

It has been a true blessing to spend all this one-on-one time with Wyatt. He is such a sweet little character. I love him so much. He is persistent in all that he sets out to do and keeps working on his independent walking. I am beyond impressed and know he will keep it up when we get home.

Wyatt and I have been making friends and keeping very busy. We continue to see the sites around Eugene. We have met some “cannamoms” that can truly relate to the challenges, the tweaking and fine-tuning of treating a child with cannabis. I am so grateful they are here.

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Work in Progress – Day 8

After seeing some great results up through day 6, we have since lost much of seizure control we originally observed. This may be due to many factors including not zeroing in on the right dosing levels or Wyatt’s metabolism, etc. (He also lost some of the positive side-effects like sleep. He was up for two hours ready to hang out and play between 2:30 and 4:30 a.m.!)

However, we still have lots of things to try and dosing tweaks we can do while we are here. We know there is still potential for cannabis to work since we saw evidence that it can reduce his seizures. Today we started cohort B (a different set of plant profiles that have evidence for treating epilepsy) at the dose that seemed to be most effective with cohort A. He is two doses in. I’ll be reporting on results in the next few days. Pray for improvement, sustainable improvement.

This tinkering with plant profiles and dosing reminds me very much of the Keto diet. (Which, if you know my experience with Keto or have administered it, it is A LOT of work.) What I like about Keto, is what I like about cannabis. There are lots of options and the ability to customize based on the patient.

I am really glad there are lots of cannabis options to trial in Oregon because different people respond to different combinations of cannabinoids.

#meetcannabis #wholeplant #hopeful

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Timing is everything

Timing is everything. Isn’t that a truism? It is definitely applies to Wyatt and cannabis.

The time it takes to metabolize food or medicine is unique to each individual but typically falls into an average range for most people. Wyatt’s cannabis begins to take a therapeutic effect after about 20 minutes. (A lot of other medicines taken orally fall into this range, too. That’s why it takes a while to experience pain relief from aspirin after you swallow it.)

That effect will last about three hours. To maintain a therapeutic level in his body, he must receive a small dose every three hours. Day and night. (Since we are using a plant extract, handy time-release mechanisms in many pharmaceuticals aren’t available.)